SourceOne, The One Source, The Only Source…

…to offer the broadest range of patented formulas and potencies with Citrus Polymethoxylated Flavones (PMF), limonoids, and advanced tocotrienols that support healthy cholesterol and triglyceride levels naturally.

We are the one, the only source to receive the Heart-Health Supplements Product innovation of the Year Award.

Cholesstrinol™ is a first in the industry. It represents natural and innovative solutions for supplement companies to efficiently, safely, and scientifically address customized formulas for a wide range of heart health concerns.

Cholesstrinol™… a patented combination of Citrus Polymethoxylated Flavones ( PMF-Source®) limonoids, and advanced tocotrienols ( TocoSource®) protected by US patents #6,251,400, #6,239,114 and #6,987,125

What is Cholesstrinol™?

  • Cholesstrinol™ is a synergistic patent protected formula that combines PMF-Source® citrus flavonoids with TocoSource® palm tocotrienols.
  • Cholesstrinol™ is an award winning platform of proprietary heart healthy formulas that tells a powerful brand story.
  • It pulls together the detailed scientific data in an easy-to-understand package for the consumer reducing, if not eliminating, the need for laborious guesswork or research on their part.
  • Branding these combinations under the name – Cholesstrinol™ – is designed to leverage their scientific basis.
  • Cholesstrinol™…More than ever, consumers demand clinically proven, safe, and effective products that support healthy cholesterol and triglyceride levels while helping to control inflammatory responses naturally.
  • Cholesstrinol™ Delivers

    • Higher potencies and broader flavonoid profiles that deliver optimal heart-health benefits.
    • Patent-pending red yeast rice formulation that target statin intolerant patients.
    • Advanced delivery systems to improve absorption and bioavailability, while broadening potential applications.
    • Customized, condition-specific formulations.
    • Patent-pending lemon bioflavonoid formulations that increase phyto-nutrient concentration.
    • Smaller, easier to swallow capsules.

    “Formalizing our exclusive partnership with Ingredients By Nature continues to allow SourceOne to offer superior citrus PMFs, limonoids, and eriocitrin and the reliability our customers have come to expect. Their technologically advanced extraction, processing, purification and testing processes result in the purest, highest quality, most bio-active citrus extracts available” – Jesse Lopez, CEO and founder of SourceOne

    “SourceOne has pioneered the commercial development globally of PMFs, and continues to lead in further enhancing the value of PMFs, limonoids and now eriocitrin in multiple formulations, broader applications and health conditions.” – Rob Brewster, President of Ingredients By Nature

    Approximately 64 million Americans suffer from cardiovascular complications, which are increasingly being observed in younger age groups, including adolescents. Consequently it is no surprise that consumers are becoming increasingly concerned about heart disease and its risk factors, including the role of high blood cholesterol levels, which cause about a third of all cases of all cardiovascular disease, resulting in nearly 17 million deaths annually. Such increased consumer awareness coupled with valid concerns about prescription drugs has driven demand for natural heart-health products. Cholesstrinol™ is a widely scoped and all-encompassing platform that provides numerous targeted and customized solutions for consumers with specific cardiovascular concerns.

    NEW ADVANCED …Cholesstrinol™ HPe (high potency) is a clinically proven proprietary combination of PMF-source® Citrus Flavones, TocoSource® Palm Tocotrienols and ErioSource™ Eriocitrin.

    Cholesstrinol™ Formulas:
    Important Features Original Citrus PMF & Tocotrienol Formula Cholesstrinol™ HPe Significant Advantages
    Patent Protection U.S. Patent 6,239,114;
    U.S. Patent 6,251,400;
    U.S. Patent 6,987,125
    U.S. Patent 6,239,114;
    U.S. Patent 6,251,400;
    U.S. Patent 6,987,125;
    U.S Patent 8,158,134;
    U.S Serial No. 61\559,174
    Broader & deeper patent protection
    Supports total Healthy LDL & Cholesterol Yes Yes
    Supports Healthy C-Reactive Protein (CRP) Levels No Studies Yes Improved 57%
    Dosage 2 Capsules Per Day 1 Capsule Per Day
    PMF-Source® Citrus Flavones 30% 65% 116%
    PMF Nobiletin Standardized 12.4% 34% 174% concentration
    PMF Tangeretin Standardized 14.2% 30% 111% higher concentration
    Tocotrienol/ Tocopherol Coplex 3.0% 7.0% 133% concentration
    Eriocitrin None Standardized 5% 500% higher concentration

    SourceOne is the recipient of the 2008 Frost & Sullivan Award for Product Innovation of the Year in the U.S. Heart Health Supplements Market for our Cholesstrinol™ family of heart healthy formulas.

    As the award states, the key factors leading to the success of Cholesstrinol™ are:

    • Understanding Consumer Concerns
    • Strong Science
    • Effective Marketing Campaign
    • Strategic Alliances

    Please click here for the full award description.

    Every product under the Cholesstrinol™ umbrella is supported by a strong platform of clinical evidence demonstrating conclusive ability to deliver a desirable range of heart-healthy benefits. These attributes may include significantly improving healthy total cholesterol and triglyceride levels, as well as healthy LDL, VLDL, and HDL cholesterol levels, providing powerful antioxidant effects, promoting the body’s natural inflammatory response, and supporting healthy blood pressure and glucose levels. In addition, Cholesstrinol™ helps regulate many of the key biomarkers associated with metabolic syndrome.

    The benefits of the ingredients in the Cholesstrinol™ family of formulas have been validated in hundreds of clinical studies. The fact is, there are thousands of studies supporting the many health benefits of both marine Omega-3 EFAs and soy based plant sterol and sterol esters. Some products claim to be “clinically proven”; however, the ingredients used in the trial are not available to the consumer. Furthermore, too often the effective dose used in the clinical trials is not the same dosage found in supplements on retail shelves. SourceOne provides a consistent and reliable supply of the science-based ingredients that make up our Cholesstrinol™ family of formulas – the same ingredients at the same effective dose used in the clinical trials.

    Also, in Alternative Therapies in Health and Medicine, November/December, 2007, Vol. 13, No. 6, published the results of several studies that combined PMF-source® and TocoSource® palm tocotrienols branded Sytrinol® that was manufactured and distributed by SourceOne from 2003-2008. The largest study of the group, a 12-week double-blind, placebo-controlled protocol with 120 subjects, resulted in significant improvements in total cholesterol (-30%), LDL (-27%), and triglycerides (-34%), compared to placebo. In addition, HDL levels increased 4%, resulting in a significant 29% improvement in the LDL:HDL ratio.*

    Please click here for the full study.

    In the table below it is clear that patented Cholesstrinol at 300mg is 10X more potent than 90% concentrated Omega-3 fish oil in supporting Healthy Triglyceride Levels Naturally.

    Healthy Triglyceride Support

    Cholesstrinol HPe™ targets different mechanisms and bio-pathways to produce synergistic results for the body’s natural promotion of healthy total cholesterol, LDL cholesterol, and triglyceride levels. Additionally, Cholesstrinol HPe™ is a powerful antioxidant with numerous heart health benefits that help maintain healthy inflammatory responses.

    Cholesterol Synthesis

A Leader In Innovation



Product Development Updates

Subscribe to our newsletter to receive important updates on natural products industry trends, innovative product developments, and new scientific research.


Thank you for subscribing to our newsletter! You should receive a welcome message in your inbox within the next few minutes.